Everybody knows the Safety Dance song, but most people have no idea what anime is used in this AMV. The anime seems to be a popular anime amongst fellow otaku though.
Song: Safety Dance - Men Without Hats
Watch on Youtube
About The AnimeStory: So the story is this... nothing. Just absolutely nothing except that it's about the life of Yukko, Mai and Mio at school and everyone around them. At first you see also Nano-chan and the mini professor, but later on they are also part of the story of the three main characters. Other than that... everything is just shorts of complete and udder randomness and chaos, full of hilarity that you'll roll on the floor laughing. Sometimes even laughing your ass off.
There is also the helvitica standard shorts, which are just complete random shorts that sometimes don't make any sense, but sometimes do. They do leave you laughing and with a WTF? face.